01 - Heat a large skillet over medium-high heat. Add ground beef and season with salt, pepper, garlic powder, and onion powder. Cook while breaking up the meat until browned and cooked through, approximately 6–8 minutes. Drain excess fat if necessary.
02 - While beef cooks, whisk together mayonnaise, ketchup, mustard, white vinegar, pickle relish, and smoked paprika in a small bowl until thoroughly combined. Set aside for serving.
03 - Divide chopped lettuce evenly among four serving bowls. Arrange cherry tomatoes, red onion slices, shredded cheddar cheese, and dill pickle slices on top of the lettuce.
04 - Distribute the seasoned ground beef evenly over each salad bowl while still warm.
05 - Generously spoon the prepared burger sauce over each bowl.
06 - Top with sliced avocado, crumbled bacon, and sesame seeds if desired. Serve immediately while beef is warm.